Investigator Studies Program (MISP): Rotavirus

Effective January 2023, the Rotavirus Investigator Studies Program (MISP) Committee will accept protocol submissions within our current areas of interest (AOI) up to August 7, 2023. This is a competitive process that will be conducted by the Rotavirus MISP Review Committee in 2023. Decisions will be made on the basis of scientific merit and strategic fit within the AOI. Please review the critical activities and abide by the timelines as outlined below. The program requests that investigators specify how they will support diversity in enrollment to include traditionally underrepresented minorities/ethnic groups.

The following areas are of interest to Investigator Studies Program Committee:

• Investigation of strategies aiming to improve vaccine efficacy or effectiveness of RotaTeq™ (especially in low income settings)


• Studies to assess the reduction of gastroenteritis in areas where RotaTeq™ is widely used, where there is sufficient health care infrastructure to assess changes in disease burden, and where such data are currently limited.


• Investigate indirect health benefits to RotaTeq™ vaccine


• Studies to assess burden of rotavirus disease in new populations


• Studies to assess serotype distribution

Please complete a protocol with detailed budget via Visiontracker, the Company's on-line study management system (in US) or your MSD country representative (outside US). The protocol will be collectively reviewed and selected by the Rotavirus MISP Review Committee.

Critical Activities and Timelines:

Activity	Review Cycle
Protocol Submission with Detailed Budget	August 7, 2023
Final Comments to Investigator	October 23, 2023

MISP Information
This site is intended for US investigators only. Investigators outside of the US interested in submitting research proposals to the Investigator Studies Program should contact their local MSD office.